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Jian Shen Selected Research

Arsenic Trioxide (Trisenox)

12/2018Arsenic trioxide reverses the chemoresistance in hepatocellular carcinoma: a targeted intervention of 14-3-3η/NF-κB feedback loop.
1/2015Inhibition of the cancer stem cells-like properties by arsenic trioxide, involved in the attenuation of endogenous transforming growth factor beta signal.
12/2014Inhibition of transforming growth factor beta/SMAD signal by MiR-155 is involved in arsenic trioxide-induced anti-angiogenesis in prostate cancer.
11/2014Inhibition of TGF-β/SMAD3/NF-κB signaling by microRNA-491 is involved in arsenic trioxide-induced anti-angiogenesis in hepatocellular carcinoma cells.
1/2004Intratumoral injection of arsenic to enhance antitumor efficacy in human esophageal carcinoma cell xenografts.
11/2003The inhibition of growth and angiogenesis in heterotransplanted esophageal carcinoma via intratumoral injection of arsenic trioxide.
4/2003Reactive oxygen species and antioxidants in apoptosis of esophageal cancer cells induced by As2O3.
4/2002Mitochondria, calcium and nitric oxide in the apoptotic pathway of esophageal carcinoma cells induced by As2O3.
2/2002Nitric oxide and calcium ions in apoptotic esophageal carcinoma cells induced by arsenite.
2/2002Morphological and functional changes of mitochondria in apoptotic esophageal carcinoma cells induced by arsenic trioxide.

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Jian Shen Research Topics

Disease

151Neoplasms (Cancer)
04/2024 - 03/2002
48Inflammation (Inflammations)
05/2024 - 08/2007
27Hepatocellular Carcinoma (Hepatoma)
11/2023 - 01/2014
23Wounds and Injuries (Trauma)
01/2024 - 04/2011
20Neoplasm Metastasis (Metastasis)
12/2023 - 11/2009
19Infections
02/2024 - 09/2010
18Lung Neoplasms (Lung Cancer)
12/2023 - 08/2010
18Hemorrhage
11/2023 - 01/2013
15Carcinoma (Carcinomatosis)
12/2023 - 02/2002
15Insulin Resistance
01/2023 - 03/2009
14Body Weight (Weight, Body)
11/2023 - 03/2005
14Thrombosis (Thrombus)
01/2022 - 06/2004
14Hemolysis
02/2020 - 10/2008
13Hypoxia (Hypoxemia)
05/2024 - 01/2012
13Stomach Neoplasms (Stomach Cancer)
01/2024 - 06/2011
13Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2021 - 09/2010
12Cardiovascular Diseases (Cardiovascular Disease)
01/2024 - 05/2008
11Metabolic Syndrome (Dysmetabolic Syndrome X)
04/2016 - 08/2007
10Breast Neoplasms (Breast Cancer)
11/2023 - 07/2015
10Esophageal Squamous Cell Carcinoma
01/2022 - 01/2011
9Prostatic Neoplasms (Prostate Cancer)
02/2024 - 08/2008
9Ischemia
01/2023 - 07/2010
9Carcinogenesis
01/2020 - 03/2002
8Colorectal Neoplasms (Colorectal Cancer)
05/2024 - 10/2018
8Heart Failure
01/2024 - 01/2016
8Adenocarcinoma of Lung
01/2024 - 09/2013
8Bacterial Infections (Bacterial Infection)
01/2024 - 11/2019
7Pathologic Constriction (Stenosis)
05/2024 - 01/2015
7Pancreatic Neoplasms (Pancreatic Cancer)
12/2022 - 07/2012
7ST Elevation Myocardial Infarction
01/2022 - 03/2015
6Acute Lung Injury
11/2023 - 10/2011
6Chronic Obstructive Pulmonary Disease (COPD)
08/2023 - 09/2012
6Fibrosis (Cirrhosis)
03/2023 - 01/2017
6Glioblastoma (Glioblastoma Multiforme)
01/2023 - 07/2020
6Reperfusion Injury
09/2022 - 07/2010
6Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 01/2012
6Type 2 Diabetes Mellitus (MODY)
12/2021 - 03/2009
6Hyperplasia
10/2021 - 04/2002
6Stroke (Strokes)
08/2019 - 05/2008
6Obesity
01/2018 - 08/2008
5Lung Injury
11/2023 - 01/2017
5Necrosis
10/2023 - 07/2010
5Hypertension (High Blood Pressure)
06/2022 - 05/2010
5Spinal Tuberculosis (Pott's Disease)
08/2021 - 06/2013
5Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
06/2021 - 07/2013
5Cerebral Infarction
08/2017 - 05/2008

Drug/Important Bio-Agent (IBA)

40Proteins (Proteins, Gene)FDA Link
05/2024 - 05/2003
25Biomarkers (Surrogate Marker)IBA
05/2024 - 08/2008
19CytokinesIBA
05/2024 - 11/2007
16Long Noncoding RNAIBA
01/2024 - 09/2013
14Anti-Bacterial Agents (Antibiotics)IBA
01/2024 - 12/2011
11MicroRNAs (MicroRNA)IBA
01/2024 - 09/2013
10LipidsIBA
04/2024 - 05/2008
10Arsenic Trioxide (Trisenox)FDA Link
12/2018 - 02/2002
9Glucose (Dextrose)FDA LinkGeneric
12/2023 - 11/2009
9CollagenIBA
12/2023 - 09/2017
9HydrogelsIBA
12/2023 - 11/2020
9CarbonIBA
12/2023 - 05/2019
91-phenyl-3,3-dimethyltriazene (PDT)IBA
07/2023 - 06/2014
9methylallyl trisulfide (MATS)IBA
01/2023 - 09/2015
9Reactive Oxygen Species (Oxygen Radicals)IBA
01/2023 - 04/2003
9Messenger RNA (mRNA)IBA
09/2022 - 06/2011
9RNA (Ribonucleic Acid)IBA
01/2022 - 08/2008
8Doxorubicin (Adriamycin)FDA LinkGeneric
12/2023 - 01/2018
8Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2023 - 02/2002
8AntigensIBA
12/2022 - 02/2014
7Interleukin-6 (Interleukin 6)IBA
11/2022 - 08/2008
6DNA (Deoxyribonucleic Acid)IBA
04/2024 - 06/2009
6EnzymesIBA
01/2024 - 01/2012
6Glutathione (Reduced Glutathione)IBA
01/2024 - 01/2020
6LipopolysaccharidesIBA
11/2023 - 10/2011
6PlatinumIBA
12/2022 - 01/2015
6Therapeutic UsesIBA
05/2022 - 12/2013
6SmokeIBA
06/2020 - 08/2010
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2024 - 03/2010
5Peroxidase (Myeloperoxidase)IBA
01/2024 - 10/2011
5CalciumIBA
01/2023 - 02/2002
5SolutionsIBA
01/2023 - 11/2003
5Indicators and Reagents (Reagents)IBA
01/2023 - 01/2020
5C-Reactive ProteinIBA
01/2023 - 05/2008
5Fatty Acids (Saturated Fatty Acids)IBA
12/2022 - 08/2007
5Insulin (Novolin)FDA Link
12/2021 - 01/2013
5AlbuminsIBA
12/2021 - 04/2017
5AnticoagulantsIBA
01/2020 - 01/2013

Therapy/Procedure

82Therapeutics
05/2024 - 01/2004
22Drug Therapy (Chemotherapy)
02/2024 - 01/2013
16Immunotherapy
05/2024 - 01/2020
10Lasers (Laser)
01/2024 - 10/2016
10Neoadjuvant Therapy
01/2022 - 10/2012
8Photothermal Therapy
12/2023 - 01/2018
8Transjugular Intrahepatic Portasystemic Shunt
11/2023 - 01/2020
8Photochemotherapy (Photodynamic Therapy)
01/2022 - 10/2012
7Stents
05/2024 - 10/2013
7Percutaneous Coronary Intervention
01/2024 - 03/2015
7Surgical Portasystemic Shunt (Portosystemic Shunt)
11/2023 - 12/2020
6Transplantation
01/2023 - 08/2002
5Operative Surgical Procedures
02/2024 - 01/2017
5Ligation
12/2023 - 04/2016
5Punctures
12/2023 - 06/2013
5Precision Medicine
01/2023 - 01/2015